1.1.1.156: glycerol 2-dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about glycerol 2-dehydrogenase (NADP+), go to the full flat file.

Reaction

glycerol
+
NADP+
=
Glycerone
+
NADPH
+
H+

Synonyms

DHA oxidoreductase, DHAR, dihydroxy (reduced nicotinamide adenine dinucleotide phosphate) reductase, dihydroxyacetone reductase, dihydroxyacetone reductase (NADPH), GDH4, GLD2, glycerol:NADP 2-oxidoreductase, dihydroxyacetone forming, NADP-dependent GLDH, NADPH-DHAR

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.156 glycerol 2-dehydrogenase (NADP+)

Inhibitors

Inhibitors on EC 1.1.1.156 - glycerol 2-dehydrogenase (NADP+)

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
-
80% inhibition at 1 mM
8-hydroxyquinoline
-
complete inhibition at 10 mM
dithiothreitol
-
25% inhibition at 10 mM
KCl
-
inhibition above 100 mM
L-cysteine
-
40% inhibition at 10 mM
Mg2+
-
40% inhibition at 5 mM
Mn2+
-
25% inhibition at 5 mM
p-chloromercuribenzoate
-
strong inhibition