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1.1.1.150: 21-hydroxysteroid dehydrogenase (NAD+)

This is an abbreviated version!
For detailed information about 21-hydroxysteroid dehydrogenase (NAD+), go to the full flat file.

Reaction

pregnan-21-ol
+
NAD+
=
pregnan-21-al
+
NADH
+
H+

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.150 21-hydroxysteroid dehydrogenase (NAD+)

Reference

Reference on EC 1.1.1.150 - 21-hydroxysteroid dehydrogenase (NAD+)

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Monder, C.; White, A.
The 21-hydroxysteroid dehydrogenases of liver. A nicotinamide adenine dinucleotide phosphate dehydrogenase and two nicotinamide adenine dinucleotide dehydrogenases
J. Biol. Chem.
240
71-77
1965
Ovis aries aries
Manually annotated by BRENDA team
Orr, J.C.; Monder, C.
The stereospecificity of the enzymatic reduction of 21-dehydrocortisol by NADH
J. Biol. Chem.
250
7547-7553
1975
Ovis aries aries
Manually annotated by BRENDA team
Orr, J.C.; Monder, C.
The stereochemistry of enzymatic reduction of 21-dehydrocortisol to cortisol
J. Steroid Biochem.
6
297-299
1975
Ovis aries aries
Manually annotated by BRENDA team
Holland, H.L.; Ninniss, R.W.; Brown, F.M.
Stereochemistry of hydrogen loss during C-21 dehydroxylation of tetrahydrodeoxycorticosterone by Eubacterium lentum
Can. J. Chem.
67
1590-1595
1989
Bos taurus, Eggerthella lenta
-
Manually annotated by BRENDA team
Keller, B.; Adamski, J.
RDH12, a retinol dehydrogenase causing Lebers congenital amaurosis, is also involved in steroid metabolism
J. Steroid Biochem. Mol. Biol.
104
190-194
2007
Homo sapiens, Mus musculus
Manually annotated by BRENDA team