18.104.22.168: 20alpha-hydroxysteroid dehydrogenase
This is an abbreviated version, for detailed information about 20alpha-hydroxysteroid dehydrogenase, go to the full flat file.
20-alpha-HSD, 20-alpha-hydroxysteroid dehydrogenase, 20alpha-HSD, 20alpha-HSDH, 20alpha-hydroxy steroid dehydrogenase, 20alpha-hydroxysteroid dehydrogenase, 20alpha-hydroxysteroid oxidoreductase, 20alpha-OH-SDH, AKR1C1, AKR1C23, AKR1C3, AKR1C5, aldo-keto reductase family 1 member C1, HSD1
pH Range on EC 22.214.171.124 - 20alpha-hydroxysteroid dehydrogenase
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5.4 - 7.6
steroid reduction e.g. 20alpha-dihydrocortisol with MES, MOPS or sodium phosphate, NADH
5.8 - 10.5
25°C, below and above range inactivation
6.3 - 9
steroid oxidation e.g. cortisol with Tris hydrochloride, NAD+
6.5 - 9
pH 6.8 favouring progesterone to 20alpha-hydroxyprogesterone reaction and pH 8.0 vice versa