1.1.1.148: estradiol 17alpha-dehydrogenase

This is an abbreviated version, for detailed information about estradiol 17alpha-dehydrogenase, go to the full flat file.

Reaction

estradiol-17alpha
+
NAD(P)+
=
estrone
+
NAD(P)H
+
H+

Synonyms

17alpha-estradiol dehydrogenase, 17alpha-HSD, 17alpha-hydroxy steroid dehydrogenase, 17alpha-hydroxy steroid oxidoreductase, 17alpha-hydroxysteroid dehydrogenase, 17alpha-hydroxysteroid oxidoreductase, estradiol 17alpha-oxidoreductase, More

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.148 estradiol 17alpha-dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.148 - estradiol 17alpha-dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
17alpha-estradiol + NAD(P)+
estrone + NAD(P)H
show the reaction diagram
17alpha-hydroxy-4-androsten-3-one + NADP+
4-androsten-3,17-dione + NADPH
show the reaction diagram
17beta-hydroxy-4-androsten-3-one + NADP+
4-androsten-3,17-dione + NADPH
show the reaction diagram
-
testosterone
-
-
?
5alpha-androstan-3beta,17alpha-diol + NADP+
3beta-hydroxy-5alpha-androstan-17-one + NADPH
show the reaction diagram
-
-
-
-
?
5alpha-dihydrotestosterone + NADPH
5alpha-androstane-3alpha,17alpha-diol + NADP+
show the reaction diagram
-
-
-
?
5alpha-pregnane-3,20-dione + NADPH + H+
3alpha,5alpha-3-hydroxypregnan-20-one + NADP+
show the reaction diagram
-
-
-
?
androstanedione + NADPH
5alpha-androstane-3-one-17alpha-ol + NADP+
show the reaction diagram
-
-
-
?
androstenedione + NADPH + H+
epitestosterone + NADP+
show the reaction diagram
-
-
-
?
androsterone + NADPH
5alpha-androstane-3alpha,17alpha-diol + NADP+
show the reaction diagram
-
-
-
?
dehydroepiandrosterone + NADPH
5-androstene-3alpha,17alpha-diol + NADP+
show the reaction diagram
-
-
-
?
estradiol-17alpha 3-galacturonide + NADP+
estrone 3-galacturonide + NADPH
show the reaction diagram
-
-
-
-
?
estradiol-17alpha 3-glucoside + NADP+
estrone 3-glucoside + NADPH
show the reaction diagram
-
-
-
-
?
estradiol-17alpha 3-glucuronide + NADP+
estrone 3-glucuronide + NADPH
show the reaction diagram
additional information
?
-