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1.1.1.148: estradiol 17alpha-dehydrogenase

This is an abbreviated version!
For detailed information about estradiol 17alpha-dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.148

Reaction

estradiol-17alpha
+
NAD(P)+
=
estrone
+
NAD(P)H
+
H+

Synonyms

17alpha-estradiol dehydrogenase, 17alpha-HSD, 17alpha-hydroxy steroid dehydrogenase, 17alpha-hydroxy steroid oxidoreductase, 17alpha-hydroxysteroid dehydrogenase, 17alpha-hydroxysteroid oxidoreductase, estradiol 17alpha-oxidoreductase, More

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.148 estradiol 17alpha-dehydrogenase

Purification

Purification on EC 1.1.1.148 - estradiol 17alpha-dehydrogenase

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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
2 forms
-
8 forms, six of them purified to homogenity: IA, IB, IC, IIC, IID, III
-
partial
-
recombinant GST-fusion enzyme from Escherichia coli strain BL21(DE3) by glutathione affinity chromatography