1.1.1.146: 11beta-hydroxysteroid dehydrogenase

This is an abbreviated version!
For detailed information about 11beta-hydroxysteroid dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.146

1.1.1.146

glucocorticoid

cortisone

mineralocorticoid

corticosterone

hypertension

obesity

adipose

fetal

adrenal

aldosterone

11-dehydrocorticosterone

pregnancy

testosterone

urinary

progesterone

carbenoxolone

visceral

dexamethasone

leydig

steroidogenic

obese

androgen

adipocytes

cushing

hexose-6-phosphate

tetrahydrocortisol

hypothalamic-pituitary-adrenal

steroidogenesis

renin

acth

glycyrrhetinic

21-hydroxylase

hsd3b1

hypercortisolism

analysis

pharmacology

pregnenolone

drug development

spironolactone

liquorice

11beta-hydroxylase

hsd17b3

androstenedione

omental

5alpha

medicine

hypokalemia

alpha-hydroxyprogesterone

thf

5alpha-reductase

alpha-hydroxysteroid

cyp11b1

11-ketotestosterone

low-renin

Reaction

Synonyms

11 beta-hydroxysteroid dehydrogenase type 1, 11-beta hydroxysteroid dehydrogenase type 1, 11-beta-HSD1, 11-beta-HSD1 (oxidase) NADP+, 11-beta-HSD2, 11-beta-hydroxysteroid dehydrogenase type1, 11-DH, 11-DH2, 11-oxoreductase, 11beta hydroxysteroid dehydrogenase type 1, 11beta-HSD, 11beta-HSD 1, 11beta-HSD type 1, 11beta-HSD-1, 11beta-HSD-2, 11beta-HSD1, 11beta-HSD1A, 11beta-HSD2, 11beta-hydroxy steroid dehydrogenase, 11beta-hydroxy steroid dehydrogenase type 2, 11beta-hydroxysteroid dehydrogenase, 11beta-hydroxysteroid dehydrogenase 1, 11beta-hydroxysteroid dehydrogenase 2, 11beta-hydroxysteroid dehydrogenase isoforms 1, 11beta-hydroxysteroid dehydrogenase type 1, 11beta-hydroxysteroid dehydrogenase type 2, 11beta-hydroxysteroid dehydrogenase type I, 11beta-hydroxysteroid dehydrogenase type-1, 11beta-hydroxysteroid dehydrogenase-1, 11beta-hydroxysteroid dehydrogenases type 1, 11beta-hydroxysteroid type 1 dehydrogenase, 11beta-hydroxysteroid-dehydrogenase type I, 11betaHSD1, 11betaHSD2, 11HSD1, beta-hydroxysteroid dehydrogenase, corticosteroid 11-reductase, corticosteroid 11beta-dehydrogenase, dehydrogenase, 11beta-hydroxy steroid, HSD1, HSD11B, HSD11B1, Hsd11B2, HSD2, hydroxysteroid (11-beta) dehydrogenase, isozyme 11beta-HSD1, More, NAD-dependent 11-beta-hydroxysteroid dehydrogenase, NADP(+)-dependent 11beta-dehydrogenase, NADP+-dependent 11beta-hydroxysteroid dehydrogenase 1, type 1 11beta-hydroxysteroid dehydrogenase

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.146 11beta-hydroxysteroid dehydrogenase

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Results	in table
22	Activating Compound
60	AA Sequence
30	Application
1	CAS Registry Number
67	Cloned(Commentary)
188	Cofactor
10	Crystallization (Commentary)
3399	Disease/ Diagnostics
18	Expression
16	General Information
1	General Stability
1306	IC50 Value
1759	Inhibitors
67	Ki Value [mM]
126	KM Value [mM]
91	Localization
8	Metals/Ions
23	Molecular Weight [Da]
214	Natural Substrates/ Products (Substrates)
299	Organism
4	Pathway
185	PDB ID
25	pH Optimum
2	pH Range
2	pH Stability
15	Posttranslational Modification
27	Protein Variants
28	Purification (Commentary)
7	Reaction
3	Reaction Type
283	Reference
362	Source Tissue
15	Specific Activity [micromol/min/mg]
7	Storage Stability
429	Substrates and Products (Substrate)
21	Subunits
396	Synonyms
1	Systematic Name
16	Temperature Optimum [°C]
1	Temperature Stability [°C]
10	Turnover Number [1/s]

Sequence

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Sequence on EC 1.1.1.146 - 11beta-hydroxysteroid dehydrogenase

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P0DKC5 pBLAST

HSD1A_ARATH

Arabidopsis thaliana

349

39087

Swiss-Prot