1.1.1.145: 3beta-hydroxy-DELTA5-steroid dehydrogenase

This is an abbreviated version, for detailed information about 3beta-hydroxy-DELTA5-steroid dehydrogenase, go to the full flat file.

Reaction

a 3beta-hydroxy-DELTA5-steroid
+
NAD+
=
a 3-oxo-DELTA5-steroid
+
NADH
+
H+

Synonyms

3-beta-hydroxy-5-ene steroid dehydrogenase, 3-beta-hydroxy-delta(5)-steroid dehydrogenase, 3-beta-hydroxysteroid dehydrogenase, 3-beta-hydroxysteroid dehydrogenase type-2, 3beta hydroxysteroid dehydrogenase, 3beta-HSD, 3beta-HSD type II, 3beta-HSD1, 3beta-HSD2, 3beta-HSD22, 3beta-HSDH, 3beta-HSD_1, 3beta-hydroxy steroid dehydrogenase/5-ene-4-ene isomerase, 3beta-hydroxy steroid dehydrogenase/isomerase, 3beta-hydroxy-5-ene steroid dehydrogenase, 3beta-hydroxy-5-ene-steroid dehydrogenase, 3beta-hydroxy-5-ene-steroid oxidoreductase, 3beta-hydroxy-DELTA5-C27-steroid dehydrogenase/isomerase, 3beta-hydroxy-DELTA5-C27-steroid oxidoreductase, 3beta-hydroxysteroid dehydrogenase, 3beta-hydroxysteroid dehydrogenase 1, 3beta-hydroxysteroid dehydrogenase 2, 3beta-hydroxysteroid dehydrogenase type 1, 3beta-hydroxysteroid dehydrogenase type 2, 3beta-hydroxysteroid dehydrogenase type 2 and, 3beta-hydroxysteroid dehydrogenase type II, 3beta-hydroxysteroid dehydrogenase type1, 3beta-hydroxysteroid dehydrogenase/DELTA5-DELAT4 isomerase type 2, 3beta-hydroxysteroid dehydrogenase/DELTA5-DELTA4 isomerase, 3beta-hydroxysteroid dehydrogenase/DELTA5-DELTA4-isomerase, 3beta-hydroxysteroid dehydrogenase/DELTA5-DELTA4-isomerase type II, 3beta-hydroxysteroid dehydrogenase/isomerase, 3beta-hydroxysteroid dehydrogenase/isomerase type 1, 3betaHSD, 3betaHSD1, 3betaHSD2, 5-ene-3-beta-hydroxysteroid dehydrogenase, 5alpha-dihydrotestosterone 3beta-hydroxysteroid dehydrogenase, dehydrogenase, 3beta-hydroxy-DELTA5-steroid, DELTA5-3beta-hydroxysteroid dehydrogenase, DHRS4, HSD2, HSD3B, HSD3B1, HSD3B2, Hsd3b6, HSDB1, HSDH, More, progesterone reductase, steroid-DELTA5-3beta-ol dehydrogenase, type 1 3beta-hydroxysteroid dehydrogenase, type 1 3beta-hydroxysteroid dehydrogenase/isomerase, type 2 3beta-hydroxysteroid dehydrogenase, type 2 3beta-hydroxysteroid dehydrogenase/isomerase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.145 3beta-hydroxy-DELTA5-steroid dehydrogenase

Turnover Number

Turnover Number on EC 1.1.1.145 - 3beta-hydroxy-DELTA5-steroid dehydrogenase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.18
(S)-1-indanol
-
pH 7.4, 25°C
0.25
(S)-1-tetralol
-
pH 7.4, 25°C
0.075
(S)-phenyl-1-butanol
-
pH 7.4, 25°C
0.88
1,4-Naphthoquinone
-
pH 7.4, 25°C
41.7
1-phenylisatin
-
pH 7.4, 25°C
0.07 - 0.15
16alpha-hydroxy-dehydroepiandrosterone
0.04 - 0.15
16beta-hydroxy-dehydroepiandrosterone
40.2
2,3-heptanedione
-
pH 7.4, 25°C
16.3
2,3-Hexanedione
-
pH 7.4, 25°C
26.7
2,3-Pentanedione
-
pH 7.4, 25°C
3.7
4,4'-dimethylbenzil
-
pH 7.4, 25°C
2
4-benzoylpyridine
-
pH 7.4, 25°C
33.3
4-hexanoylpyridine
-
pH 7.4, 25°C
16.7
4-Nitrobenzaldehyde
-
pH 7.4, 25°C
0.097
5alpha-androstane-3,17-dione
-
pH 7.4, 25°C
0.095
5alpha-dihydrotestosterone
-
pH 7.4, 25°C
0.083
5beta-androstan-17beta-ol-3-one
-
pH 7.4, 25°C
0.017
5beta-androstan-3beta-ol-17-one
-
pH 7.4, 25°C
0.077
5beta-androstane-3,17-dione
-
pH 7.4, 25°C
0.017
5beta-androstane-3beta,17beta-diol
-
pH 7.4, 25°C
0.07
5beta-pregnan-20alpha-ol-3-one
-
pH 7.4, 25°C
0.041
5beta-Pregnan-3beta-ol-20-one
-
pH 7.4, 25°C
0.063
5beta-pregnane-3,20-dione
-
pH 7.4, 25°C
0.014
5beta-pregnane-3beta,20alpha-diol
-
pH 7.4, 25°C
2
6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione
-
pH 7.4, 25°C
11.8
9,10-phenanthrenequinone
-
pH 7.4, 25°C
0.05
all-trans-retinal
-
pH 7.4, 25°C
0.0233
allopregnanolone
-
-
0.0333
androstenediol
-
-
31.7
benzil
-
pH 7.4, 25°C
0.02 - 11.6
dehydroepiandrosterone
0.043
Dehydrolithocholic acid
-
pH 7.4, 25°C
28.3
diacetyl
-
pH 7.4, 25°C
33.3
dimethyl-2-oxo-glutarate
-
pH 7.4, 25°C
2.7
hexanophenone
-
pH 7.4, 25°C
31.7
isatin
-
pH 7.4, 25°C
0.65
menadione
-
pH 7.4, 25°C
0.85
n-butyrophenone
-
pH 7.4, 25°C
0.02 - 0.187
NAD+
0.31 - 1.65
NADH
0.04 - 1.48
pregnenolone
4.7
Pyridine-4-aldehyde
-
pH 7.4, 25°C
2
valerophenone
-
pH 7.4, 25°C