1.1.1.140: sorbitol-6-phosphate 2-dehydrogenase

This is an abbreviated version, for detailed information about sorbitol-6-phosphate 2-dehydrogenase, go to the full flat file.

Reaction

D-sorbitol 6-phosphate
+
NAD+
=
D-fructose 6-phosphate
+
NADH
+
H+

Synonyms

D-glucitol-6-phosphate dehydrogenase, D-sorbitol-6-phosphate 2-dehydrogenase, D-sorbitol-6-phosphate dehydrogenase, dehydrogenase, D-sorbitol 6-phosphate, Glucitol-6-phosphate dehydrogenase, GutF, GutM, GutR, ketosephosphate reductase, MdS6PDH, More, operon gutFRMCBA, S6PDH, sorbitol-6-P-dehydrogenase, sorbitol-6-phosphate dehydrogenase, Stl6PDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.140 sorbitol-6-phosphate 2-dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.140 - sorbitol-6-phosphate 2-dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
D-dulcitol 6-phosphate + NAD+
?
show the reaction diagram
-
at 3% of reaction reaction with sorbitol 6-phosphate
-
-
?
D-fructose 6-phosphate + NADH
D-sorbitol 6-phosphate + NAD+
show the reaction diagram
-
-
-
-
r
D-fructose 6-phosphate + NADH + H+
D-sorbitol 6-phosphate + NAD+
show the reaction diagram
-
sorbitol is not detected when Stl6PDH is not overexpressed
-
-
?
D-sorbitol 6-phosphate + NAD+
D-fructose 6-phosphate + NADH + H+
show the reaction diagram
D-sorbitol 6-phosphate + NADP+
D-fructose 6-phosphate + NADPH + H+
show the reaction diagram
mannitol 1-phosphate + NAD+
?
show the reaction diagram
-
at 1-5% of reaction with sorbitol 6-phosphate
-
-
?