1.1.1.138: mannitol 2-dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about mannitol 2-dehydrogenase (NADP+), go to the full flat file.

Reaction

D-mannitol
+
NADP+
=
D-fructose
+
NADPH
+
H+

Synonyms

Cla h 8, Cla h 8 allergen, D-mannitol 2-dehydrogenase, D-mannitol dehydrogenase, D-mannitol dehydrogenase, NADP-dependent, LRMDH, LXR1, MAD1p, Mannitol 2-dehydrogenase [NADP+], mannitol dehydrogenase, mannitol dehydrogenase (NADP+), mannitol dehydrogenase (nicotinamide dinucleotide phosphate), mannitol dehydrogenase 1, MDH, More, MtDH, NADP-dependent mannitol dehydrogenase, NADP-dependent MtDH, NADP-mannitol dehydrogenase, PIG8p, PSLDR, TbMDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.138 mannitol 2-dehydrogenase (NADP+)

Substrates Products

Substrates Products on EC 1.1.1.138 - mannitol 2-dehydrogenase (NADP+)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1-deoxy-6-methyl-D-glucitol + NADP+
1-deoxy-6-methyl-D-glucose + NADPH
show the reaction diagram
-
poorer substrate than D-glucitol
-
?
1-deoxy-6-methyl-D-mannitol + NADP+
1-deoxy-6-methyl-D-fructose + NADPH
show the reaction diagram
-
poorer substrate than D-mannitol
-
?
1-deoxy-D-glucitol + NADP+
1-deoxy-D-glucose + NADPH
show the reaction diagram
-
poorer substrate than glucitol
-
?
1-deoxy-D-mannitol + NADP+
1-deoxy-D-fructose + NADPH
show the reaction diagram
-
poorer substrate than D-mannitol
-
?
arabinose + NADPH + H+
arabinitol + NADP+
show the reaction diagram
-
-
-
-
r
D-arabinitol + NADP+
D-xylulose + NADPH + H+
show the reaction diagram
D-fructose + NADPH
D-mannitol + NADP+
show the reaction diagram
D-fructose + NADPH + H+
D-mannitol + NADP+
show the reaction diagram
D-mannitol + 3-acetylpyridine adenine dinucleotide phosphate
D-fructose + 3-acetylpyridine adenine dinucleotide phosphate(H)
show the reaction diagram
-
7.5% of the activity compared to NADP+
-
?
D-mannitol + NAD(P)+
D-fructose + NAD(P)H + H+
show the reaction diagram
D-mannitol + NAD+
D-fructose + NADH + H+
show the reaction diagram
D-mannitol + NADP+
D-fructose + NADPH + H+
show the reaction diagram
D-mannitol + thio-NADP+
D-fructose + thio-NADPH
show the reaction diagram
-
30% of the activity compared to NADP+
-
?
D-mannose + NADPH + H+
D-mannitol + NADP+
show the reaction diagram
-
-
-
-
r
D-sorbitol + NADP+
D-sorbose + NADPH + H+
show the reaction diagram
L-arabinitol + NADP+
L-xylulose + NADPH + H+
show the reaction diagram
L-sorbitol + NADP+
L-sorbose + NADPH
show the reaction diagram
L-sorbitol + NADP+
L-sorbose + NADPH + H+
show the reaction diagram
-
21% of the activity with D-mannitol
-
-
r
perseitol + NADP+
? + NADPH
show the reaction diagram
-
6% of the activity compared to D-mannitol
-
?
ribose + NADPH + H+
ribitol + NADP+
show the reaction diagram
-
-
-
-
r
xylose + NADPH + H+
xylitol + NADP+
show the reaction diagram
-
-
-
-
r
additional information
?
-