1.1.1.138: mannitol 2-dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about mannitol 2-dehydrogenase (NADP+), go to the full flat file.

Reaction

D-mannitol
+
NADP+
=
D-fructose
+
NADPH
+
H+

Synonyms

Cla h 8, Cla h 8 allergen, D-mannitol 2-dehydrogenase, D-mannitol dehydrogenase, D-mannitol dehydrogenase, NADP-dependent, LRMDH, LXR1, MAD1p, Mannitol 2-dehydrogenase [NADP+], mannitol dehydrogenase, mannitol dehydrogenase (NADP+), mannitol dehydrogenase (nicotinamide dinucleotide phosphate), mannitol dehydrogenase 1, MDH, More, MtDH, NADP-dependent mannitol dehydrogenase, NADP-dependent MtDH, NADP-mannitol dehydrogenase, PIG8p, PSLDR, TbMDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.138 mannitol 2-dehydrogenase (NADP+)

Specific Activity

Specific Activity on EC 1.1.1.138 - mannitol 2-dehydrogenase (NADP+)

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.4
-
recombinant enzyme, forward reaction
0.5 - 0.9
-
crude enzyme extract, optimization of culture conditions, overview
0.54
-
pH 9.0, 30C
0.61
-
crude recombinant Escherichia coli cell extract
1
-
recombinant enzyme, reverse reaction
3.1
-
substrate D-fructose + NADH, pH 7.5, 37C
3.2
-
substrate arabinose, pH 7.5, 37C
5.1
-
substrate xylose, pH 7.5, 37C
5.2
-
substrate ribose, pH 7.5, 37C
6.1
-
substrate D-mannose, pH 7.5, 37C
9.1
-
substrate D-mannitol, pH 7.5, 37C
124.6
-
purified recombinant enzyme
277
purified native enzyme
315
-
substrate D-fructose + NADPH, pH 7.5, 37C
331
-
pH 5.5, 30C
350
purified native enzyme
additional information