1.1.1.133: dTDP-4-dehydrorhamnose reductase

This is an abbreviated version, for detailed information about dTDP-4-dehydrorhamnose reductase, go to the full flat file.

Reaction

dTDP-beta-L-rhamnose
+
NADP+
=
dTDP-4-dehydro-beta-L-rhamnose
+
NADPH
+
H+

Synonyms

4-ketoreductase, bifunctional UDP-4-keto-6-deoxy-D-glucose epimerase/reductase, dTDP-4-dehydrorhamnose reductase, dTDP-4-keto-L-rhamnose reductase, dTDP-4-keto-rhamnose reductase, dTDP-4-ketorhamnose reductase, dTDP-6-deoxy-L-lyxo-4-hexulose reductase, dTDP-6-deoxy-L-mannose dehydrogenase, dTDP-L-rhamnose synthetase, RmlD, TDP-4-keto-rhamnose reductase, TDP-4-ketorhamnose reductase, thymidine diphosphate-4-dehydrorhamnose reductase, thymidine diphosphate-6-deoxy-L-talose, thymidine diphospho-4-ketorhamnose reductase, UGER

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.133 dTDP-4-dehydrorhamnose reductase

IC50 Value

IC50 Value on EC 1.1.1.133 - dTDP-4-dehydrorhamnose reductase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0021
2,6,7-trihydroxy-9-(2-hydroxyphenyl)-3H-xanthen-3-one
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.0015
2,6,7-trihydroxy-9-methyl-3H-xanthen-3-one
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.0009
2,6,7-trihydroxy-9-phenyl-3H-xanthen-3-one
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.0025
5-ethenyl-1-methyl-9,10-dihydrophenanthrene-2,7-diol
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication