1.1.1.127: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase

This is an abbreviated version, for detailed information about 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase, go to the full flat file.

Reaction

2-dehydro-3-deoxy-D-gluconate
+
NAD+
=
(4S)-4,6-dihydroxy-2,5-dioxohexanoate
+
NADH
+
H+

Synonyms

2-keto-3-deoxy-D-gluconate (3-deoxy-D-glycero-2,5-hexodiulosonic acid) dehydrogenase, 2-keto-3-deoxy-D-gluconate dehydrogenase, 2-keto-3-deoxygluconate (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase, 2-keto-3-deoxygluconate 5-dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.127 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase

Reference

Reference on EC 1.1.1.127 - 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Condemine, G.; Hugouvieux-Cotte-Pattat, N.; Robert-Baudouy, J.
An enzyme in the pectinolytic pathway of Erwinia chrysanthemi: 2-Keto-3-deoxygluconate oxidoreductase
J. Gen. Microbiol.
130
2839-2844
1984
Dickeya chrysanthemi
-
Manually annotated by BRENDA team
Preiss, J.; Ashwell, G.
Polygalacturonic acid metabolism in bacteria. II. Formation and metabolism of 3-deoxy-D-glycero-2,5-hexodiulosonic acid
J. Biol. Chem.
238
1577-1583
1963
Pseudomonas sp.
Manually annotated by BRENDA team