1.1.1.123: sorbose 5-dehydrogenase (NADP+)
This is an abbreviated version!
For detailed information about sorbose 5-dehydrogenase (NADP+), go to the full flat file.
Reaction
Synonyms
5-keto-D-fructose reductase, 5-ketofructose reductase, AJA48273.1, CP-AKR, reduced nicotinamide adenine dinucleotide phosphate-linked reductase, sorbose (nicotinamide adenine dinucleotide phosphate) dehydrogenase
ECTree
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Engineering
Engineering on EC 1.1.1.123 - sorbose 5-dehydrogenase (NADP+)
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additional information
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addition of Arg and loss of Asp decrease the electric potential of the adenosine ribose-binding-pocket, creating an environment favorable for NADPH-binding, the replacement of an Asp with an Ala and the adjacent Leu with an Arg change the potential