1.1.1.121: aldose 1-dehydrogenase (NAD+)

This is an abbreviated version, for detailed information about aldose 1-dehydrogenase (NAD+), go to the full flat file.

Reaction

D-aldose
+
NAD+
=
D-aldonolactone
+
NADH
+
H+

Synonyms

aldohexose dehydrogenase, aldose dehydrogenase, AldT, D-aldohexose dehydrogenase, dehydrogenase, D-aldohexose, More, Ta0754, TAD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.121 aldose 1-dehydrogenase (NAD+)

Engineering

Engineering on EC 1.1.1.121 - aldose 1-dehydrogenase (NAD+)

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ENGINEERING
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D242N
mutation results in a large decrease in thermostability of TAD without dissociation into dimer or monomer
F141A
mutation results in decrease in thermostability of TAD without dissociation into dimer or monomer
F249A
mutation results in decrease in thermostability of TAD without dissociation into dimer or monomer