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1.1.1.120: galactose 1-dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about galactose 1-dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.1.1.120

Reaction

D-galactose
+
NADP+
=
D-galactono-1,5-lactone
 +
NADPH
 +
H+

Synonyms

abequosedehydrogenase, AraDH, D-galactose dehydrogenase (NADP+), galactose-1DH, L-arabinose/D-galactose 1-dehydrogenase, NADP-galactose-1-dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.120 galactose 1-dehydrogenase (NADP+)

Substrates Products

Substrates Products on EC 1.1.1.120 - galactose 1-dehydrogenase (NADP+)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2,6-dideoxy-D-allofuranose + NADP+
? + NADPH
show the reaction diagram
-
i.e. digitoxose, furanose form, 81% of the activity compared to abequose
-
?
2,6-dideoxy-D-allose + NADP+
?
show the reaction diagram
-
81% activity compared to 3,6-dideoxy-D-galactose
-
-
r
2-deoxy-D-galactose + NADP+
D-galactonolactone + NADPH
show the reaction diagram
2-deoxy-D-ribose + NADP+
? + NADPH
show the reaction diagram
-
18% of the activity compared to abequose
-
?
3,6-dideoxy-beta-D-galactofuranose + NADP+
3,6-dideoxy-D-galactono-1,4-lactone + NADPH
show the reaction diagram
-
i.e. abequose, furanose form, beta-configuration
-
?
3,6-dideoxy-D-galactose + NADP+
?
show the reaction diagram
-
100% activity
-
-
r
3-deoxy-D-galactose + NADP+
D-galactonolactone + NADPH
show the reaction diagram
-
36% of the activity compared to abequose
-
?
6-deoxy-D-galactose + NADP+
D-galactonolactone + NADPH
show the reaction diagram
alpha,beta-L-arabinose + NADP+
L-arabinolactone + NADPH
show the reaction diagram
alpha-D-galactose + NADP+
D-galactonolactone + NADPH
show the reaction diagram
-
39% of the activity compared to alpha,beta-D-galactose and alpha,beta-L-arabinose
product is assumed to be the corresponding -1,5-lactone
?
beta-D-galactofuranose + NADP+
D-galactono-1,4-lactone + NADPH
show the reaction diagram
beta-D-galactose + NADP+
D-galatonolactone + NADPH
show the reaction diagram
-
-
product is assumed to be the corresponding -1,5-lactone
?
beta-L-arabinose + NADP+
L-arabinolactone + NADPH
show the reaction diagram
D-arabinose + NADP+
D-arabinolactone + NADPH
show the reaction diagram
-
5% of the activity compared to abequose
-
?
D-fucose + NAD+
?
show the reaction diagram
-
-
-
-
?
D-fucose + NADP+
?
show the reaction diagram
-
100% activity
-
-
?
D-galactose + NAD+
D-galactono-1,5-lactone + NADH + H+
show the reaction diagram
-
-
-
-
?
D-galactose + NADP+
D-galactono-1,5-lactone + NADPH + H+
show the reaction diagram
-
69% activity compared to D-fucose
-
-
?
D-galactose + NADP+
D-galactonolactone + NADPH
show the reaction diagram
D-ribose + NADP+
? + NADPH
show the reaction diagram
-
traces of activity
-
?
L-arabinose + NAD+
L-arabino-1,5-lactone + NADH + H+
show the reaction diagram
-
-
-
-
?
L-arabinose + NADP+
?
show the reaction diagram
-
12% activity compared to D-fucose
-
-
?
L-arabinose + NADP+
L-arabino-1,5-lactone + NADPH + H+
show the reaction diagram
L-arabinose + NADP+
L-arabinolactone + NADPH
show the reaction diagram
-
6% of the compared to abequose
-
?
additional information
?
-
-
some minor activity (about 1%) can be measured with D-xylose and L-lyxose, while no activity is detected with D-glucose or L-rhamnose
-
-
?