1.1.1.12: L-arabinitol 4-dehydrogenase

This is an abbreviated version, for detailed information about L-arabinitol 4-dehydrogenase, go to the full flat file.

Reaction

L-arabinitol
+
NAD+
=
L-xylulose
+
NADH
+
H+

Synonyms

dehydrogenase, L-arabinitol, L-arabitol dehydrogenase, LAD, pentitol-DPN dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.12 L-arabinitol 4-dehydrogenase

Reference

Reference on EC 1.1.1.12 - L-arabinitol 4-dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Chiang, C.; Knight, S.G.
A new pathway of pentose metabolism
Biochem. Biophys. Res. Commun.
3
554-559
1960
Penicillium chrysogenum
Manually annotated by BRENDA team
Witteveen, C.F.B.; Busink, R.; Van de Vondervoort, P.; Dijkema, C.; Swart, K.; Visser, J.
L-Arabinose and D-xylose catabolism in Aspergillus niger
J. Gen. Microbiol.
135
2163-2171
1989
Aspergillus niger
-
Manually annotated by BRENDA team
De Vries, R.P.; Flipphi, M.J.A.; Witteveen, C.F.B.; Visser, J.
Characterization of an Aspergillus nidulans L-arabitol dehydrogenase mutant
FEMS Microbiol. Lett.
123
83-90
1994
Aspergillus nidulans
Manually annotated by BRENDA team
Chiang, C.; Knight, S.G.
L-Arabinose metabolism by cell-free extracts of Penicillium chrysogenum
Biochim. Biophys. Acta
46
271-278
1961
Penicillium chrysogenum
Manually annotated by BRENDA team
Seiboth, B.; Hartl, L.; Pail, M.; Kubicek, C.P.
D-xylose metabolism in Hypocrea jecorina: loss of the xylitol dehydrogenase step can be partially compensated for by lad1-encoded L-arabinitol-4-dehydrogenase
Eukaryot. Cell
2
867-875
2003
Trichoderma reesei
Manually annotated by BRENDA team
Pail, M.; Peterbauer, T.; Seiboth, B.; Hametner, C.; Druzhinina, I.; Kubicek, C.P.
The metabolic role and evolution of L-arabinitol 4-dehydrogenase of Hypocrea jecorina
Eur. J. Biochem.
271
1864-1872
2004
Trichoderma reesei
Manually annotated by BRENDA team
de Groot, M.J.; Prathumpai, W.; Visser, J.; Ruijter, G.J.
Metabolic control analysis of Aspergillus niger L-arabinose catabolism
Biotechnol. Prog.
21
1610-1616
2005
Aspergillus niger
Manually annotated by BRENDA team
Suzuki, T.; Tran, L.H.; Yogo, M.; Idota, O.; Kitamoto, N.; Kawai, K.; Takamizawa, K.
Cloning and expression of NAD+-dependent L-arabinitol 4-dehydrogenase gene (ladA) of Aspergillus oryzae
J. Biosci. Bioeng.
100
472-474
2005
Aspergillus oryzae, Aspergillus oryzae (Q763T4)
Manually annotated by BRENDA team
Sullivan, R.; Zhao, H.
Cloning, characterization, and mutational analysis of a highly active and stable L-arabinitol 4-dehydrogenase from Neurospora crassa
Appl. Microbiol. Biotechnol.
77
845-852
2007
Neurospora crassa
Manually annotated by BRENDA team
Fonseca, C.; Romao, R.; Rodrigues de Sousa, H.; Hahn-Hagerdal, B.; Spencer-Martins, I.
L-Arabinose transport and catabolism in yeast
FEBS J.
274
3589-3600
2007
Candida arabinofermentans, Candida arabinofermentans PYCC, Meyerozyma guilliermondii, Meyerozyma guilliermondii PYCC 3012
Manually annotated by BRENDA team
Fonseca, C.; Neves, A.R.; Antunes, A.M.; Noronha, J.P.; Hahn-Haegerdal, B.; Santos, H.; Spencer-Martins, I.
Use of in vivo 13C nuclear magnetic resonance spectroscopy to elucidate L-arabinose metabolism in yeasts
Appl. Environ. Microbiol.
74
1845-1855
2008
Candida arabinofermentans, Candida arabinofermentans PYCC 5603T, Meyerozyma guilliermondii, Meyerozyma guilliermondii PYCC 3012
Manually annotated by BRENDA team
Rutten, L.; Ribot, C.; Trejo-Aguilar, B.; Woesten, H.A.; de Vries, R.P.
A single amino acid change (Y318F) in the L-arabitol dehydrogenase (LadA) from Aspergillus niger results in a significant increase in affinity for D-sorbitol
BMC Microbiol.
9
166
2009
Aspergillus niger (A2QAC0), Aspergillus niger
Manually annotated by BRENDA team
Kim, B.; Sullivan, R.P.; Zhao, H.
Cloning, characterization, and engineering of fungal L-arabinitol dehydrogenases
Appl. Microbiol. Biotechnol.
87
1407-1414
2010
Aspergillus niger (A2QAC0), Penicillium chrysogenum (B6HI95), Penicillium chrysogenum Wisconsin 54-1255 (B6HI95), Trichoderma reesei (Q96V44)
Manually annotated by BRENDA team
Fernandes, S.; Tuohy, M.G.; Murray, P.G.
Cloning, heterologous expression, and characterization of the xylitol and L-arabitol dehydrogenase genes, Texdh and Telad, from the thermophilic fungus Talaromyces emersonii
Biochem. Genet.
48
480-495
2010
Rasamsonia emersonii (C5J3R8)
Manually annotated by BRENDA team
Akel, E.; Metz, B.; Seiboth, B.; Kubicek, C.P.
Molecular regulation of arabinan and L-arabinose metabolism in Hypocrea jecorina (Trichoderma reesei)
Eukaryot. Cell
8
1837-1844
2009
Trichoderma reesei (Q96V44)
Manually annotated by BRENDA team
Bae, B.; Sullivan, R.P.; Zhao, H.; Nair, S.K.
Structure and engineering of L-arabinitol 4-dehydrogenase from Neurospora crassa
J. Mol. Biol.
402
230-240
2010
Neurospora crassa, Neurospora crassa (Q7SI09)
Manually annotated by BRENDA team
Tiwari, M.; Lee, J.K.
Molecular modeling studies of L-arabinitol 4-dehydrogenase of Hypocrea jecorina: its binding interactions with substrate and cofactor
J. Mol. Graph. Model.
28
707-713
2010
Trichoderma reesei (Q96V44), Trichoderma reesei
Manually annotated by BRENDA team