1.1.1.12: L-arabinitol 4-dehydrogenase
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For detailed information about L-arabinitol 4-dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.12
Reaction
Synonyms
ADH, dehydrogenase, L-arabinitol, HjLAD, L-arabinitol dehydrogenase, L-arabitol dehydrogenase, LAD, Lad1, LADA, More, NAD(P)+-dependent arabitol dehydrogenase, pentitol-DPN dehydrogenase, XYL2
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Reference on EC 1.1.1.12 - L-arabinitol 4-dehydrogenase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Chiang, C.; Knight, S.G.
A new pathway of pentose metabolism
Biochem. Biophys. Res. Commun.
3
554-559
1960
Penicillium chrysogenum
Witteveen, C.F.B.; Busink, R.; Van de Vondervoort, P.; Dijkema, C.; Swart, K.; Visser, J.
L-Arabinose and D-xylose catabolism in Aspergillus niger
J. Gen. Microbiol.
135
2163-2171
1989
Aspergillus niger
-
De Vries, R.P.; Flipphi, M.J.A.; Witteveen, C.F.B.; Visser, J.
Characterization of an Aspergillus nidulans L-arabitol dehydrogenase mutant
FEMS Microbiol. Lett.
123
83-90
1994
Aspergillus nidulans
Chiang, C.; Knight, S.G.
L-Arabinose metabolism by cell-free extracts of Penicillium chrysogenum
Biochim. Biophys. Acta
46
271-278
1961
Penicillium chrysogenum
Seiboth, B.; Hartl, L.; Pail, M.; Kubicek, C.P.
D-xylose metabolism in Hypocrea jecorina: loss of the xylitol dehydrogenase step can be partially compensated for by lad1-encoded L-arabinitol-4-dehydrogenase
Eukaryot. Cell
2
867-875
2003
Trichoderma reesei
Pail, M.; Peterbauer, T.; Seiboth, B.; Hametner, C.; Druzhinina, I.; Kubicek, C.P.
The metabolic role and evolution of L-arabinitol 4-dehydrogenase of Hypocrea jecorina
Eur. J. Biochem.
271
1864-1872
2004
Trichoderma reesei
de Groot, M.J.; Prathumpai, W.; Visser, J.; Ruijter, G.J.
Metabolic control analysis of Aspergillus niger L-arabinose catabolism
Biotechnol. Prog.
21
1610-1616
2005
Aspergillus niger
Suzuki, T.; Tran, L.H.; Yogo, M.; Idota, O.; Kitamoto, N.; Kawai, K.; Takamizawa, K.
Cloning and expression of NAD+-dependent L-arabinitol 4-dehydrogenase gene (ladA) of Aspergillus oryzae
J. Biosci. Bioeng.
100
472-474
2005
Aspergillus oryzae (Q763T4), Aspergillus oryzae
Sullivan, R.; Zhao, H.
Cloning, characterization, and mutational analysis of a highly active and stable L-arabinitol 4-dehydrogenase from Neurospora crassa
Appl. Microbiol. Biotechnol.
77
845-852
2007
Neurospora crassa
Fonseca, C.; Romao, R.; Rodrigues de Sousa, H.; Hahn-Hagerdal, B.; Spencer-Martins, I.
L-Arabinose transport and catabolism in yeast
FEBS J.
274
3589-3600
2007
Meyerozyma guilliermondii, [Candida] arabinofermentans, Meyerozyma guilliermondii PYCC 3012, [Candida] arabinofermentans PYCC 5603
Fonseca, C.; Neves, A.R.; Antunes, A.M.; Noronha, J.P.; Hahn-Haegerdal, B.; Santos, H.; Spencer-Martins, I.
Use of in vivo 13C nuclear magnetic resonance spectroscopy to elucidate L-arabinose metabolism in yeasts
Appl. Environ. Microbiol.
74
1845-1855
2008
Meyerozyma guilliermondii, [Candida] arabinofermentans, [Candida] arabinofermentans PYCC 5603T, Meyerozyma guilliermondii PYCC 3012
Rutten, L.; Ribot, C.; Trejo-Aguilar, B.; Woesten, H.A.; de Vries, R.P.
A single amino acid change (Y318F) in the L-arabitol dehydrogenase (LadA) from Aspergillus niger results in a significant increase in affinity for D-sorbitol
BMC Microbiol.
9
166
2009
Aspergillus niger (A2QAC0), Aspergillus niger
Kim, B.; Sullivan, R.P.; Zhao, H.
Cloning, characterization, and engineering of fungal L-arabinitol dehydrogenases
Appl. Microbiol. Biotechnol.
87
1407-1414
2010
Aspergillus niger (A2QAC0), Penicillium chrysogenum (B6HI95), Trichoderma reesei (Q96V44), Penicillium chrysogenum Wisconsin 54-1255 (B6HI95)
Fernandes, S.; Tuohy, M.G.; Murray, P.G.
Cloning, heterologous expression, and characterization of the xylitol and L-arabitol dehydrogenase genes, Texdh and Telad, from the thermophilic fungus Talaromyces emersonii
Biochem. Genet.
48
480-495
2010
Rasamsonia emersonii (C5J3R8)
Akel, E.; Metz, B.; Seiboth, B.; Kubicek, C.P.
Molecular regulation of arabinan and L-arabinose metabolism in Hypocrea jecorina (Trichoderma reesei)
Eukaryot. Cell
8
1837-1844
2009
Trichoderma reesei (Q96V44), Trichoderma reesei
Bae, B.; Sullivan, R.P.; Zhao, H.; Nair, S.K.
Structure and engineering of L-arabinitol 4-dehydrogenase from Neurospora crassa
J. Mol. Biol.
402
230-240
2010
Neurospora crassa (Q7SI09), Neurospora crassa
Tiwari, M.; Lee, J.K.
Molecular modeling studies of L-arabinitol 4-dehydrogenase of Hypocrea jecorina: its binding interactions with substrate and cofactor
J. Mol. Graph. Model.
28
707-713
2010
Trichoderma reesei (Q96V44), Trichoderma reesei
Mahmud, A.; Hattori, K.; Hongwen, C.; Kitamoto, N.; Suzuki, T.; Nakamura, K.; Takamizawa, K.
NAD+-dependent xylitol dehydrogenase (xdhA) and L-arabitol-4-dehydrogenase (ladA) deletion mutants of Aspergillus oryzae for improved xylitol production
Biotechnol. Lett.
35
769-777
2013
Aspergillus oryzae (Q763T4), Aspergillus oryzae, Aspergillus oryzae KBN616 (Q763T4)
Sukpipat, W.; Komeda, H.; Prasertsan, P.; Asano, Y.
Purification and characterization of xylitol dehydrogenase with L-arabitol dehydrogenase activity from the newly isolated pentose-fermenting yeast Meyerozyma caribbica 5XY2
J. Biosci. Bioeng.
123
20-27
2016
Meyerozyma caribbica (A0A1B4XTS0), Meyerozyma caribbica, Meyerozyma caribbica 5XY2 (A0A1B4XTS0), Meyerozyma caribbica 5XY2
Singh, R.K.; Tiwari, M.K.; Singh, R.; Haw, J.R.; Lee, J.K.
Immobilization of L-arabinitol dehydrogenase on aldehyde-functionalized silicon oxide nanoparticles for L-xylulose production
Appl. Microbiol. Biotechnol.
98
1095-1104
2014
Trichoderma reesei (Q96V44), Trichoderma reesei, Trichoderma reesei YSM 768 (Q96V44)
Tiwari, M.K.; Singh, R.K.; Gao, H.; Kim, T.; Chang, S.; Kim, H.S.; Lee, J.K.
pH-rate profiles of L-arabinitol 4-dehydrogenase from Hypocrea jecorina and its application in L-xylulose production
Bioorg. Med. Chem. Lett.
24
173-176
2014
Trichoderma reesei (Q96V44), Trichoderma reesei, Trichoderma reesei YSM 768 (Q96V44)
Nikolaev, I.; Farmer Hansen, S.; Madrid, S.; de Vries, R.P.
Disruption of the L-arabitol dehydrogenase encoding gene in Aspergillus tubingensis results in increased xylanase production
Biotechnol. J.
8
905-911
2013
Aspergillus tubingensis (H6WCP4), Aspergillus tubingensis (JQ079782), Aspergillus tubingensis, Aspergillus tubingensis 1M-7 (H6WCP4)
Mahmud, A.; Hattori, K.; Hongwen, C.; Kitamoto, N.; Suzuki, T.; Nakamura, K.; Takamizawa, K.
Xylitol production by NAD+-dependent xylitol dehydrogenase (xdhA)- and L-arabitol-4-dehydrogenase (ladA)-disrupted mutants of Aspergillus oryzae
J. Biosci. Bioeng.
115
353-359
2013
Aspergillus oryzae (Q763T4), Aspergillus oryzae P5 (Q763T4)
Ryu, S.; Trinh, C.T.
Understanding functional roles of native pentose-specific transporters for activating dormant pentose metabolism in Yarrowia lipolytica
Appl. Environ. Microbiol.
84
e02146-17
2018
Yarrowia lipolytica, Yarrowia lipolytica ATCC MYA-2613
Sukpipat, W.; Komeda, H.; Prasertsan, P.; Asano, Y.
Purification and characterization of xylitol dehydrogenase with L-arabitol dehydrogenase activity from the newly isolated pentose-fermenting yeast Meyerozyma caribbica 5XY2
J. Biosci. Bioeng.
123
20-27
2017
Meyerozyma caribbica (A0A1B4XTS0), Meyerozyma caribbica, Meyerozyma caribbica 5XY2 (A0A1B4XTS0), Meyerozyma caribbica 5XY2
Patel, S.; Otari, S.; Chan Kang, Y.; Lee, J.
Protein-inorganic hybrid system for efficient his-tagged enzymes immobilization and its application in l-xylulose production
RSC Adv.
7
3488-3494
2017
Trichoderma reesei (Q96V44)
-
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