1.1.1.108: carnitine 3-dehydrogenase

This is an abbreviated version, for detailed information about carnitine 3-dehydrogenase, go to the full flat file.

Reaction

carnitine
+
NAD+
=
3-dehydrocarnitine
+
NADH
+
H+

Synonyms

Cdh, CDHA, CDHB, CDHC, CDHR, L-(-)-carnitine dehydrogenase, L-carnitine dehydrogenase, L-CDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.108 carnitine 3-dehydrogenase

Inhibitors

Inhibitors on EC 1.1.1.108 - carnitine 3-dehydrogenase

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3-deydrocarnitine
-
competitive inhibition vs. L-carnitine
5,5'-dithiobis(2-nitrobenzoate)
-
-
Cu+
-
60-70% inhibition
Hydrazine hydrate
-
30 mM, 70% inhibition
hydroxylamine
-
1 mM, complete inhibition
NADH
-
competitive inhibition vs. NAD+
Ni2+
-
strong inhibition
o-phenanthroline
-
38% inhibition
p-chloromercuribenzoate
Sodium borate
-
20 mM, 60% inhibition
trimethylamine
-
L-carnitine dehydrogenase, strong inhibition