1.1.1.103: L-threonine 3-dehydrogenase

This is an abbreviated version, for detailed information about L-threonine 3-dehydrogenase, go to the full flat file.

Reaction

L-threonine
+
NAD+
=
L-2-amino-3-oxobutanoate
+
NADH
+
H+

Synonyms

CLOST_1621, L-ThrDH, L-threonine dehydrogenase, More, orf382, TDG, TDH, Thr dehydrogenase, ThrDH, threonine 3-dehydrogenase, threonine dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.103 L-threonine 3-dehydrogenase

pH Range

pH Range on EC 1.1.1.103 - L-threonine 3-dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6 - 12
activity range, pH-dependent activity varies in different buffer systems, profile overview
7.4 - 9
-
-
8.5
74% of maximum activity
9.2 - 12
-
22% of maximal activity at pH 9.2, 50% at pH 9.5, and 52% at pH 12.0
10.5
31% of maximum activity
additional information
-
pH dependencies of wild-type enzyme and E152D mutant, overview