1.1.1.103: L-threonine 3-dehydrogenase

This is an abbreviated version, for detailed information about L-threonine 3-dehydrogenase, go to the full flat file.

Reaction

L-threonine
+
NAD+
=
L-2-amino-3-oxobutanoate
+
NADH
+
H+

Synonyms

CLOST_1621, L-ThrDH, L-threonine dehydrogenase, More, orf382, TDG, TDH, Thr dehydrogenase, ThrDH, threonine 3-dehydrogenase, threonine dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.103 L-threonine 3-dehydrogenase

pH Optimum

pH Optimum on EC 1.1.1.103 - L-threonine 3-dehydrogenase

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
8.2 - 8.8
-
-
8.4
-
C38D mutant enzyme, stimulated with 5 mM Zn2+
8.5 - 8.9
-
-
8.6 - 8.7
-
30% activity at pH 7.5, 80% activity at pH 9.8
9
-
crude enzyme extracts from mitochondria frozen for 14 days and dialyzed
10.1
-
wild-type enzyme