1.1.1.102: 3-dehydrosphinganine reductase

This is an abbreviated version, for detailed information about 3-dehydrosphinganine reductase, go to the full flat file.

Reaction

sphinganine
+
NADP+
=
3-dehydrosphinganine
+
NADPH
+
H+

Synonyms

3-KDS reductase, 3-ketodihydrosphingosine reductase, 3-ketosphinganine reductase, 3-oxosphinganine reductase, 3-oxosphinganine:NADPH oxidoreductase, 3KDSR, D-3-dehydrosphinganine reductase, D-3-oxosphinganine reductase, D-3-oxosphinganine:B-NADPH oxidoreductase, DSR, FVT-1, Fvt1, h-FTV-1, KDS reductase, Ksr1p, KsrA, m-FTV-1, More, TSC10, TSC10A, Tsc10p

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.102 3-dehydrosphinganine reductase

Natural Substrates Products

Natural Substrates Products on EC 1.1.1.102 - 3-dehydrosphinganine reductase

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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(S)-2-amino-1-hydroxyoctadecane-3-one + NADPH
(S)-2-amino-1-(R)-3-dihydroxyoctadecane + NADP+
show the reaction diagram
-
enzyme acts at the cytoplasmic side of endoplasmic reticulum
-
?
2-amino-1-hydroxyoctadecane-3-one + NADPH
2-amino-1,3-dihydroxyoctadecane + NADP+
show the reaction diagram
-
-
-
?
3-dehydrosphinganine + NADPH
sphinganine + NADP+
show the reaction diagram
3-oxosphinganine + NADPH + H+
D-erythro-dihydrosphingosine + L-threo-dihydrosphingosine + NADP+
show the reaction diagram
3-oxosphinganine + NADPH + H+
dihydrosphingosine + NADP+
show the reaction diagram
S4SCP5
-
-
-
?