1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase

This is an abbreviated version, for detailed information about 3-oxoacyl-[acyl-carrier-protein] reductase, go to the full flat file.

Reaction

a (3R)-3-hydroxyacyl-[acyl-carrier protein]
+
NADP+
=
a 3-oxoacyl-[acyl-carrier protein]
+
NADPH
+
H+

Synonyms

3-ketoacyl acyl carrier protein reductase, 3-ketoacyl-(acyl-carrier-protein) reductase, 3-ketoacyl-ACP reductase, 3-ketoacyl-ACP(CoA) reductase, 3-ketoacyl-acyl carrier protein reductase, 3-ketoacyl-[acyl-carrier-protein] reductase, 3-oxoacyl-(acyl carrier protein) reductase, 3-oxoacyl-ACP reductase, 3-oxoacyl-AcpM reductase, 3-oxoacyl-thioester reductase, 3-oxoacyl-[ACP]reductase, ACP reductase, beta-ketoacyl acyl carrier protein (ACP) reductase, beta-ketoacyl acyl carrier protein reductase, beta-ketoacyl reductase, beta-ketoacyl thioester reductase, beta-ketoacyl-ACP reductase, beta-ketoacyl-acyl carrier protein reductase, beta-ketoacyl-[acyl carrier protein] reductase, beta-ketoacyl-[acyl-carrier protein] (ACP) reductase, BKR, FabG, FabG1, fabG4, KACPR, KCR1, KCR2, MabA, NADPH-specific 3-oxoacyl-[acylcarrier protein]reductase, OAR, Oar1p, PHA-specific acetoacetyl-CoA reductase, PhaB, polyhydroxyalkanoate-specific acetoacetyl coenzyme A reductase, reductase, 3-oxoacyl-[acyl carrier protein], RhlG

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase

IC50 Value

IC50 Value on EC 1.1.1.100 - 3-oxoacyl-[acyl-carrier-protein] reductase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.45
(E)-2-nitrophenyl cinnamate
Escherichia coli
P0AEK2
pH 7.0
0.18
(E)-4-cyanophenyl 3-(benzo[d][1,3]dioxol-5-yl)acrylate
Escherichia coli
P0AEK2
pH 7.0
0.18
(E)-phenyl 3-(benzo[d][1,3]dioxol-5-yl)acrylate
Escherichia coli
P0AEK2
pH 7.0
0.5
4-acetoxyanthecotulide
Plasmodium falciparum K1
-
pH 7.0, 25C
0.75
4-hydroxyanthecotulide
Plasmodium falciparum K1
-
pH 7.0, 25C
1
anthecotulide
Plasmodium falciparum K1
-
pH 7.0, 25C
0.01
Bithionol
Plasmodium falciparum
Q86RB1
over 75% inhibition at 0.02 mM, IC50: 0.010 mM
0.0154
bromochlorophen
Plasmodium falciparum
Q86RB1
an anthelmintic agent, over 75% inhibition at 0.02 mM, IC50: 0.0154 mM
0.881 - 0.948
chlorogenic acid
Escherichia coli
-
IC50: 0.881-0.948 mM
0.0038
di-resorcinol sulfide
Plasmodium falciparum
Q86RB1
over 75% inhibition at 0.02 mM, IC50: 0.0038 mM
0.00554 - 0.1223
epigallocatechin gallate
0.002
Hexachlorophene
Plasmodium falciparum
Q86RB1
an anthelmintic and antimicrobial agent, over 75% inhibition at 0.02 mM, IC50: 0.002 mM
0.0212
kaempferol
synthetic construct
-
pH 7.0
0.215
N-(1,3-dioxoisoindolin-2-yl)-2-oxo-2H-chromene-3-carboxamide
Escherichia coli
P0AEK2
pH 7.0
0.3048
quercetin
synthetic construct
-
pH 7.0
0.00078
Tannic acid
Escherichia coli
-
-
additional information
grape skin extract
-